c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis
The c-Myc-PANK3-EMT axis plays a critical role in preserving the structure and function of intestinal barrier. PANK3 is a potential target and folic acid is a candidate agonist of PANK3 to repair intestinal barrier in UC.
Authors
- Xinqiang Ji (ORCID: https://orcid.org/0000-0001-5618-5428)
- Nan Aa
- Guangji Wang (ORCID: https://orcid.org/0000-0002-0777-3896)
- Tian Cheng (ORCID: https://orcid.org/0000-0002-3540-8247)
- Shize Zhang
- Jiye Aa (ORCID: https://orcid.org/0000-0001-5096-4025)
- Yuang Chen (ORCID: https://orcid.org/0000-0001-8733-3948)
- Song Zhao (ORCID: https://orcid.org/0000-0001-9206-4711)
- Mengqin Wang (ORCID: https://orcid.org/0000-0001-7460-4307)
- Xu Chen (ORCID: https://orcid.org/0000-0002-5166-083X)
- Yaohui Wang (ORCID: https://orcid.org/0000-0003-0153-4277)
- Yi Wang (ORCID: https://orcid.org/0000-0002-6074-0532)
- Yuan Xie (ORCID: https://orcid.org/0000-0002-4901-146X)
- Jun Xiao (ORCID: https://orcid.org/0000-0002-6142-9914)
- Tao Xie (ORCID: https://orcid.org/0000-0002-6837-9243)
- Hong Yu (ORCID: https://orcid.org/0009-0003-0783-9650)
Institutions
- Nanjing University of Chinese Medicine (CN)
- China Pharmaceutical University (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jare.2025.12.007
- Primary Topic
- Protein Kinase Regulation and GTPase Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00