LAX1 as a core biomarker in Alzheimer’s disease and periodontitis via the STAT signaling pathway
LAX1 gates STAT-dependent neuroinflammation and periodontal destruction, offering a druggable checkpoint and blood-based biomarker for these convergent chronic diseases.
Authors
- Yang Bao
- Dongmei Cheng
- Han Guo (ORCID: https://orcid.org/0000-0002-6386-4100)
- Fang Xue (ORCID: https://orcid.org/0000-0002-4512-1960)
- Tianyuan Guo
- Zhiyong Zhang
- Xue Wang (ORCID: https://orcid.org/0009-0000-5701-361X)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12877-025-06865-x
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 0.00