Effect of infusion solutions on circulating blood volume through different administration routes in animal models of peritonitis

Conclusions: 1. Administration of 0.9% sodium chloride and 10% albumin solutions in experimental peritonitis in animals results in an increase in circulating blood volume (CBV) when administered by the intraosseous route, with increases of 30% (Р≤0.01) and 45% (Р≤0.001), respectively. 2. The 10% albumin solution, administered extraperitoneally as a bolus infusion, significantly enhanced the secretion of neutral red dye into the perfusate, which correlated with its effects on CBV and improved microcirculation in the gastric mucosa.