Longitudinal Choriocapillaris and Retinal Vascular Flow Changes on OCTA with Progression to Advanced AMD

In iAMD eyes progressing to GA, CC ischemia was detectable before GA onset, with subsequent retinal VD loss after GA development. In iAMD eyes progressing to nAMD, CC ischemia developed concurrent with neovascularization. OCTA-derived CC and retinal flow metrics may serve as non-invasive biomarkers to stratify iAMD eyes at risk for progression.

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Publication Details

Journal
Clinical ophthalmology
Published
2025-12-01
DOI
https://doi.org/10.2147/opth.s562717
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Longitudinal Choriocapillaris and Retinal Vascular Flow Changes on OCTA with Progression to Advanced AMD

Sophie Lee, Glenn Yiu, Kareem Moussa, Susanna S. Park et al.
Clinical ophthalmology
Retinal Diseases and Treatments
article

Longitudinal Choriocapillaris and Retinal Vascular Flow Changes on OCTA with Progression to Advanced AMD

Sophie Lee, Glenn Yiu, Kareem Moussa, Susanna S. Park, Parisa Emami-Naeini, Samuel Feldman, Ala Moshiri, Mohammad Mehdi Johari Moghadam, Fateme Montazeri
article en

Abstract

In iAMD eyes progressing to GA, CC ischemia was detectable before GA onset, with subsequent retinal VD loss after GA development. In iAMD eyes progressing to nAMD, CC ischemia developed concurrent with neovascularization. OCTA-derived CC and retinal flow metrics may serve as non-invasive biomarkers to stratify iAMD eyes at risk for progression.

Clinical ophthalmologyVol. Volume 19
University of California, Davis (US)
University of California, Davis
Openalex Percentile: Top 46%
Retinal Diseases and Treatments
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