Recurrent Disseminated Talaromycosis Mimicking Liver Disease in a STAT3-Mutated HIES Patient: A Case Report
Disseminated talaromycosis should be considered in immunocompromised patients presenting with unexplained fever, hepatosplenomegaly, or organ dysfunction, even in the absence of classic symptoms. Integration of mNGS into diagnostic workflows enhances pathogen detection, and long-term antifungal prophylaxis may be necessary in patients with persistent immune deficiencies.
Authors
- Lin Yang (ORCID: https://orcid.org/0000-0002-7594-3770)
- Fei Shi (ORCID: https://orcid.org/0000-0002-9082-9140)
- Minjian Wu (ORCID: https://orcid.org/0000-0002-7500-241X)
- Furong Zeng
- Hongtao Chen (ORCID: https://orcid.org/0000-0002-9181-790X)
- Dongyuan Xie
- Yiying Zhang
Institutions
- Southern University of Science and Technology (CN)
- Shenzhen Sixth People's Hospital (CN)
- ShenZhen People’s Hospital (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/idr.s557331
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sanming Project of Medicine in Shenzhen