Imposter behind the eye: spheno-ethmoidal mucocele mimicking meningocele with compressive optic neuropathy

A male patient in his mid-30s presented with progressive right eye proptosis and vision loss, accompanied by retro-orbital and occipital pain. He had a history of skull base trauma and endoscopic repair for cerebrospinal fluid rhinorrhoea 7 years earlier. Imaging revealed a lesion adjacent to a cribriform plate defect, initially suggesting a non-expanding meningocele. However, intraoperatively, the lesion was identified as a spheno-ethmoidal mucocele with orbital extension. Endoscopic drainage and marsupialisation were performed, resulting in immediate resolution of proptosis and marked improvement in visual acuity. Follow-up imaging showed no residual lesion or optic nerve compression. This case illustrates a rare spheno-ethmoidal mucocele presenting as compressive optic neuropathy, emphasising the need for a broad differential diagnosis and multidisciplinary collaboration when evaluating skull base lesions.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-267011
Primary Topic
Sinusitis and nasal conditions
Type
article
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article

Imposter behind the eye: spheno-ethmoidal mucocele mimicking meningocele with compressive optic neuropathy

Saurabh Maheshwari, Sean James, Ajit Singh, Varun Jerath
BMJ Case Reports
Sinusitis and nasal conditions
article

Imposter behind the eye: spheno-ethmoidal mucocele mimicking meningocele with compressive optic neuropathy

Saurabh Maheshwari, Sean James, Ajit Singh, Varun Jerath
article en

Abstract

A male patient in his mid-30s presented with progressive right eye proptosis and vision loss, accompanied by retro-orbital and occipital pain. He had a history of skull base trauma and endoscopic repair for cerebrospinal fluid rhinorrhoea 7 years earlier. Imaging revealed a lesion adjacent to a cribriform plate defect, initially suggesting a non-expanding meningocele. However, intraoperatively, the lesion was identified as a spheno-ethmoidal mucocele with orbital extension. Endoscopic drainage and marsupialisation were performed, resulting in immediate resolution of proptosis and marked improvement in visual acuity. Follow-up imaging showed no residual lesion or optic nerve compression. This case illustrates a rare spheno-ethmoidal mucocele presenting as compressive optic neuropathy, emphasising the need for a broad differential diagnosis and multidisciplinary collaboration when evaluating skull base lesions.

BMJ Case ReportsVol. 18(12)
Army Hospital Research and Referral (IN)
Openalex Percentile: Top 44%
Sinusitis and nasal conditions
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Imposter behind the eye: spheno-ethmoidal mucocele mimicking meningocele with compressive optic neuropathy — Saurabh Maheshwari, Sean James, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS