Challenging the age barrier: comparative outcomes in octogenarian and non-octogenarian colorectal cancer patients

Octogenarians with non-metastatic CRC can achieve favorable treatment outcomes comparable to or even better than younger patients, supporting the feasibility of curative-intent treatment in this age group. Age alone should not preclude standard oncologic management in elderly CRC patients. However, the single-center design and modest sample size limit generalizability, and further multicenter validation is required.