Outcomes of Patients With Autosomal Dominant Polycystic Kidney Disease Prescribed SGLT2 Inhibitors in British Columbia: A Single-Arm Retrospective Cohort Study
In this cohort of 17 patients with ADPKD on SGLT2i, we did not observe any signs of adverse kidney outcomes and only two instances of GU infections occurred, neither requiring emergency visits or hospitalization. More high-quality evidence is needed to determine the safety and efficacy of SGLT2i in this population.
Authors
- Mohammad Atiquzzaman (ORCID: https://orcid.org/0000-0002-0243-7666)
- Chandi Karunarathna
- Adeera Levin (ORCID: https://orcid.org/0000-0003-2438-8401)
- Alessandro Cau (ORCID: https://orcid.org/0000-0003-3803-7784)
- Alexandra Romann
- Micheli Bevilacqua (ORCID: https://orcid.org/0000-0001-8321-7413)
- Mark Elliott (ORCID: https://orcid.org/0000-0003-0725-150X)
- Ognjenka Djurdjev
Institutions
- BC Cancer Agency (CA)
- University of British Columbia (CA)
Publication Details
- Journal
- Canadian Journal of Kidney Health and Disease
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1177/20543581251404101
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00