Low CDX2 expression and its clinicopathological associations in colorectal adenocarcinoma: prognostic insights from a retrospective cross-sectional study in Vietnam
Low CDX2 expression is linked to aggressive pathological features and advanced tumor stage in CRC, highlighting its clinicopathological associations. Semi-quantitative evaluation of CDX2 using both staining ratio and intensity provides a more informative assessment that may aid risk stratification and guide clinical decision-making in CRC patients.
Authors
- Hanh Thi Tuyet Ngo
- Tram Ho Ngoc Le (ORCID: https://orcid.org/0009-0009-5380-978X)
- Thao Thi Thu Luu (ORCID: https://orcid.org/0009-0006-8369-7676)
- Thang Quoc Pham
- Giang Huong Tran (ORCID: https://orcid.org/0000-0002-9480-4602)
- Huy Minh Le (ORCID: https://orcid.org/0000-0003-3738-0580)
- Thien Thanh Ly (ORCID: https://orcid.org/0009-0006-7773-1321)
Institutions
- University of Medicine and Pharmacy at Ho Chi Minh City (VN)
- Hong Bang International University (VN)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s13000-025-01734-y
- Citations
- 1
- Primary Topic
- Digestive system and related health
- Type
- article
- Field-Weighted Citation Impact
- 1.82