Changes in oxidative stress and inflammation biomarkers in the pathogenesis of migraine: possible relationships with lipid metabolism

This study demonstrates a statistically significant association between elevated oxidative stress (increased MDA, decreased GSH), altered inflammatory response (elevated CRP, reduced NLRP3), and migraine. Differences between MWA and MWoA suggest subtype-specific pathophysiological mechanisms. Although this study supports a potential link between oxidative stress, inflammation, and lipid metabolism in migraine, they do not establish causality. These biomarkers may represent targets for future diagnostic and therapeutic strategies.