Associations of life course social determinants of health, social mobility with cognitive function and roles of social participation and lifestyle: a multicohort study
Lifelong social disadvantage and downward mobility were associated with lower cognitive function and faster decline. While promoting healthy lifestyles and social engagement may partly mitigate theses effects, comprehensive interventions addressing adverse SDOH across the lifespan are still important for reducing cognitive aging inequities.
Authors
- Bo Xie (ORCID: https://orcid.org/0000-0002-3834-4074)
- Dongshan Zhu
- Xiang Li (ORCID: https://orcid.org/0000-0003-2395-888X)
- Chunying Fu (ORCID: https://orcid.org/0000-0003-1809-9742)
- Zhongxuan Wang (ORCID: https://orcid.org/0000-0003-1664-4639)
- Luyi Zhang
- Qi Wang (ORCID: https://orcid.org/0000-0002-8879-7151)
- Xiaoyu Zhang (ORCID: https://orcid.org/0009-0000-0849-5579)
Institutions
- Shandong University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12916-025-04510-3
- Primary Topic
- Health disparities and outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China