Increased extracellular volume, reduced stress perfusion, and worse systolic function in Wilson’s disease
In this study, stable WD patients without apparent cardiac symptoms have early signs of diffuse fibrosis, coronary microvascular dysfunction, and worse systolic function. However, this study is limited by small sample size limiting further subgroup analysis, lack of both longitudinal clinical data and biopsies, not allowing for correlation of CMR findings to histopathology.
Authors
- Andreas Kindmark (ORCID: https://orcid.org/0000-0002-2650-5926)
- Jannike Nickander (ORCID: https://orcid.org/0000-0001-5659-8142)
- Peter Kellman (ORCID: https://orcid.org/0000-0002-9875-6070)
- Csenge Fogarasi
- Rebecka Steffen Johansson
Institutions
- National Institutes of Health (US)
- National Heart, Lung, and Blood Institute (US)
Publication Details
- Journal
- Journal of Cardiovascular Magnetic Resonance
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1016/j.jocmr.2025.102669
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00