Fibulin-5 promotes fibroblast activation through LTBP-4 to improve the pathogenesis of hemorrhoids
FBLN5 and LTBP-4 play significant roles in activating fibroblasts and contributing to the pathogenesis of hemorrhoid disease. Targeting these proteins could provide novel therapeutic approaches to enhance the outcomes of hemorrhoid treatment.
Authors
- Muchun Liao
- Yuning Wu
- Feng Sun
- Ke Xiao (ORCID: https://orcid.org/0000-0001-8958-3297)
- Danqing Li (ORCID: https://orcid.org/0000-0002-7332-5143)
- Rui-Jun Xie
- Yongchang Zhao
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Guangdong Baiyun University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12876-025-04540-4
- Primary Topic
- Anorectal Disease Treatments and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00