Elucidating the role of PBRM1 in NPC via RNA-seq transcriptomic sequencing

This study illuminates PBRM1's tumor suppressor role, highlighting the AKT-mTOR pathway and aerobic glycolysis as potential therapeutic targets in NPC.

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Publication Details

Journal
SLAS TECHNOLOGY
Published
2025-12-12
DOI
https://doi.org/10.1016/j.slast.2025.100386
Primary Topic
PI3K/AKT/mTOR signaling in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Elucidating the role of PBRM1 in NPC via RNA-seq transcriptomic sequencing

Wenhai Sun, Yu Tang, Yue Ren, Qiu Qin et al.
SLAS TECHNOLOGY
PI3K/AKT/mTOR signaling in cancer
article

Elucidating the role of PBRM1 in NPC via RNA-seq transcriptomic sequencing

Wenhai Sun, Yu Tang, Yue Ren, Qiu Qin, Xiufeng Yang, Xiaojiang Li, Xinxin Wu
article en

Abstract

This study illuminates PBRM1's tumor suppressor role, highlighting the AKT-mTOR pathway and aerobic glycolysis as potential therapeutic targets in NPC.

SLAS TECHNOLOGYVol. 36
Zunyi Medical University (CN), Kunming Medical University (CN)
Openalex Percentile: Top 64%
PI3K/AKT/mTOR signaling in cancer
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