Poecilobdella manillensis ameliorates atherosclerosis by inhibiting endothelial cell pyroptosis
Both in vivo and in vitro studies have confirmed that P.manillensis ameliorates endothelial damage and inflammatory responses in AS, with involvement of the PI3K/AKT and NF-κB signaling pathways.
Authors
- Yudong Rao
- Guorong Deng (ORCID: https://orcid.org/0000-0001-5804-1356)
- Lin Yang (ORCID: https://orcid.org/0000-0001-8954-9494)
- Yiran Feng (ORCID: https://orcid.org/0000-0003-3968-051X)
- Hui Zhou (ORCID: https://orcid.org/0000-0002-6318-894X)
- Chunxia Guo
- Ying Zhang (ORCID: https://orcid.org/0000-0002-8828-0873)
- Xueya Zhang (ORCID: https://orcid.org/0000-0002-4628-3849)
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Atherosclerosis Plus
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1016/j.athplu.2025.12.004
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00