Polygenic risk score predicts pathologically confirmed cerebral amyloid angiopathy
CAA-PRS is generated. CAA-PRS is associated with pathologically confirmed CAA. CAA-PRS is associated with CAA in individuals with high amyloid burden.
Authors
- Sang-Yun Kim (ORCID: https://orcid.org/0000-0002-2952-5404)
- Jung‐Min Pyun (ORCID: https://orcid.org/0000-0002-8391-5729)
- Kwangsik Nho
- Young Ho Park (ORCID: https://orcid.org/0000-0002-2756-1786)
Institutions
- Indiana University Health (US)
- Seoul National University Bundang Hospital (KR)
- Alzheimer’s Disease Neuroimaging Initiative (US)
- Indiana Clinical and Translational Sciences Institute (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz.70958
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- Alzheimer's Association
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- National Institutes of Health