The PLAN trial: precision treatment of lumbar spine surgery with advanced nerve root blockade – protocol for a prospective, investigator-initiated, randomized non-inferiority trial
This trial seeks to provide high-quality evidence on the effectiveness of integrating selective nerve root blocks to guide surgical decompression or avoid surgery in treating lumbar radiculopathy. The findings aim to inform clinical decision-making and optimize patient outcomes. TRIAL REGISTRATION: Clinicaltrials.gov registration NCT06143813. Registration date November 9, 2023. Last update May 2, 2024, version 1.1.
Authors
- P.A. Andersen
- Hanne Dinesen
- B Uhrbrand
- Ronni Mikkelsen (ORCID: https://orcid.org/0000-0002-0010-5123)
- Mette Katrine Schulz
- Mikkel Mylius Rasmussen (ORCID: https://orcid.org/0000-0002-4768-7255)
- Mathias Møller Thygesen (ORCID: https://orcid.org/0000-0002-6544-8450)
- Jakob Gram Carlsen
- David Kocemba (ORCID: https://orcid.org/0009-0007-1075-7364)
Institutions
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Vejle Sygehus (DK)
- Danish Pain Research Center (DK)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12891-025-09395-0
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00