Orthologous genes of the red flour beetle Tribolium castaneum and the vinegar fly Drosophila melanogaster

We made use of the reference proteomes of Tribolium castaneum and Drosophila melanogaster to infer phylogenetic orthology using the OrthoFinder platform, and employed the eggNOG 6.0 database and manual phylogenetic tree analyses to assess our results. Our analysis identified more than 9,000 orthologous genes between Drosophila and Tribolium. We posit that this comprehensive list is a valuable resource for comparative studies among these insect species, such as single-cell sequencing or large-scale gene function comparisons. The results are open-access and freely available for download or interactive exploration in iBeetleBase.

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Publication Details

Journal
BMC Genomic Data
Published
2025-12-12
DOI
https://doi.org/10.1186/s12863-025-01397-0
Primary Topic
Developmental Biology and Gene Regulation
Type
article
Field-Weighted Citation Impact
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article

Orthologous genes of the red flour beetle Tribolium castaneum and the vinegar fly Drosophila melanogaster

Noel Cabañas, Gregor Bucher, Doğa Cedden
BMC Genomic Data
Developmental Biology and Gene Regulation
article

Orthologous genes of the red flour beetle Tribolium castaneum and the vinegar fly Drosophila melanogaster

Noel Cabañas, Gregor Bucher, Doğa Cedden
article en

Abstract

We made use of the reference proteomes of Tribolium castaneum and Drosophila melanogaster to infer phylogenetic orthology using the OrthoFinder platform, and employed the eggNOG 6.0 database and manual phylogenetic tree analyses to assess our results. Our analysis identified more than 9,000 orthologous genes between Drosophila and Tribolium. We posit that this comprehensive list is a valuable resource for comparative studies among these insect species, such as single-cell sequencing or large-scale gene function comparisons. The results are open-access and freely available for download or interactive exploration in iBeetleBase.

BMC Genomic DataVol. 27(1)
Max Planck Institute for Biophysical Chemistry (DE), University of Göttingen (DE)
Openalex Percentile: Top 64%
Developmental Biology and Gene Regulation
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