Impact of High‐Dose Tafamidis on Hereditary <scp>ATTR</scp> ( <scp>ATTRv</scp> ) Amyloidosis With Central Nervous System Involvement: Two Case Reports With Clinical, Radiological and Cerebrospinal Fluid Follow Up
In our two patients, progression of CNS disease occurred whilst on high-dose tafamidis, highlighting the importance of further studies into the monitoring and treatment of CNS manifestations of ATTRv.
Authors
- Mary M. Reilly (ORCID: https://orcid.org/0000-0003-0686-905X)
- Victor Jia Wei Zhang (ORCID: https://orcid.org/0000-0001-5951-4151)
- Chandrashekar Hoskote (ORCID: https://orcid.org/0009-0006-4284-1520)
- Ata Siddiqui (ORCID: https://orcid.org/0000-0002-1820-9705)
- Laura Mantoan Ritter (ORCID: https://orcid.org/0000-0003-1406-6118)
- Julian D. Gillmore (ORCID: https://orcid.org/0000-0001-6174-9232)
- Michael Peter Lunn (ORCID: https://orcid.org/0000-0003-3174-6027)
Institutions
- King's College London (GB)
- The Royal Free Hospital (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- King's College Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- Journal of the Peripheral Nervous System
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/jns.70088
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00