Distal Femoral Replacement Versus Open Reduction and Internal Fixation in Elderly Distal Femur Fractures: A Systematic Review and Meta-Analysis
Distal femur fractures are a major cause of morbidity and mortality among older adults, often complicated by osteoporosis and comorbidities that hinder recovery. This systematic review and meta-analysis compared distal femoral replacement (DFR) and open reduction internal fixation (ORIF) for such fractures in elderly patients. A comprehensive search of PubMed, Scopus, Google Scholar, and the Cochrane Library identified six comparative studies including 688 patients. Pooled data showed a trend toward fewer reoperations with DFR (odds ratio (OR): 0.44, 95% confidence interval (CI): 0.16-1.21) and similar complication rates between DFR and ORIF (OR: 0.96, 95% CI: 0.37-2.54). Mortality was significantly lower in patients treated with DFR (OR: 0.32, 95% CI: 0.12-0.84). These findings suggest that DFR may reduce mortality and the need for revision surgery without increasing complications, supporting its consideration as an alternative option for elderly patients with distal femur fractures.
Authors
- Palwasha Khan (ORCID: https://orcid.org/0000-0002-0873-8355)
- Mohamed Noureldin
- Mohamed Gamal El‐Din (ORCID: https://orcid.org/0000-0001-8443-476X)
- Ahmed El‐Hussein (ORCID: https://orcid.org/0000-0002-6349-3282)
- Symeon Naoum (ORCID: https://orcid.org/0000-0001-9582-9142)
- Ahmed Hamada
- Hagar Teama
- Ahmed Elkohail
Institutions
- Kafrelsheikh University (EG)
- Maidstone and Tunbridge Wells NHS Trust (GB)
- Princess Royal University Hospital (GB)
- Southend University Hospital NHS Foundation Trust (GB)
- Royal Devon and Exeter Hospital (GB)
- Royal Berkshire NHS Foundation Trust (GB)
- Tunbridge Wells Hospital (GB)
- University Hospitals Sussex NHS Foundation Trust (GB)
Publication Details
- Journal
- Cureus
- Published
- 2025-12-11
- DOI
- https://doi.org/10.7759/cureus.99012
- Primary Topic
- Bone fractures and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00