Effects of autoregulated and non-autoregulated blood flow restriction on vastus medialis oblique responses during low-load resistance exercise

These findings suggest that BFR training, regardless of autoregulated pressure application during exercise, produces acute physiological responses such as muscle swelling, localized <b>hypoxia</b>, and hemoconcentration that are conducive to initiating a stimulus that could elicit muscle hypertrophy in a training program. Although elevated perceptual demands accompanied these responses, the minimized mechanical joint stress supports the use of BFR as a clinically relevant alternative to high-load resistance training for individuals with limited tolerance to mechanical loading.

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Publication Details

Journal
Frontiers in Sports and Active Living
Published
2025-12-12
DOI
https://doi.org/10.3389/fspor.2025.1712606
Primary Topic
Cardiovascular and exercise physiology
Type
article
Field-Weighted Citation Impact
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article

Effects of autoregulated and non-autoregulated blood flow restriction on vastus medialis oblique responses during low-load resistance exercise

Nicholas Rolnick, Michael C. Rabel, Masoud Azadi Moghaddam, Tim Werner
Frontiers in Sports and Active Living
Cardiovascular and exercise physiology
article

Effects of autoregulated and non-autoregulated blood flow restriction on vastus medialis oblique responses during low-load resistance exercise

Nicholas Rolnick, Michael C. Rabel, Masoud Azadi Moghaddam, Tim Werner
article en

Abstract

These findings suggest that BFR training, regardless of autoregulated pressure application during exercise, produces acute physiological responses such as muscle swelling, localized <b>hypoxia</b>, and hemoconcentration that are conducive to initiating a stimulus that could elicit muscle hypertrophy in a training program. Although elevated perceptual demands accompanied these responses, the minimized mechanical joint stress supports the use of BFR as a clinically relevant alternative to high-load resistance training for individuals with limited tolerance to mechanical loading.

Frontiers in Sports and Active LivingVol. 7
Manhattan Institute for Policy Research (US), Northwell Health (US), University of Maryland Eastern Shore (US), Salisbury University (US)
Openalex Percentile: Top 44%
Cardiovascular and exercise physiology
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