Tobacco-specific nitrosamine exposure from electronic cigarettes versus combustible cigarettes: an ad hoc analysis within a systematic review of emission studies

These results suggest that switching to exclusive e-cigarette use can lead to a significant reduction in exposure to key tobacco-specific nitrosamines. This study also reinforces the importance of articulating this evidence with clarity, precision, and balance, recognizing both the substantial benefits of reduced exposure and the residual uncertainties that only long-term studies will resolve.