Polydopamine‐Functionalized Zinc Oxide Nanoparticles as a Root Canal Sealer: Characterization, Biological, and Physicochemical Properties

The outcomes of this study highlighted that the PDA@ZnO NP sealer demonstrated superior sealing ability, enhanced dentinal tubule penetration, and favorable cytocompatibility, comparable to AH Plus and more favorable than ZOE at early timepoints. It also showed strong antibacterial efficacy and improved physicochemical properties. These findings suggest that PDA@ZnO NP sealer may serve as a promising alternative for clinical endodontic applications, potentially contributing to improved treatment outcomes and long-term success in root canal therapy.