From Constitution to Disease: MicroRNA Signatures for the Early Prediction and Targeted Prevention of Polycystic Ovary Syndrome
These findings elucidate shared miRNA regulatory mechanisms between phlegm-damp constitution and PCOS, highlighting hsa-miR-24-2-5p and hsa-miR-33a-5p as pivotal mediators in this pathological transition. This provides molecular evidence for the TCM "constitution-disease correlation" theory and identifies potential targets for the prevention and treatment of PCOS.
Authors
- Huiling Qu (ORCID: https://orcid.org/0000-0003-0909-6267)
- Na Shi (ORCID: https://orcid.org/0000-0003-1564-2236)
- Lu Jiang (ORCID: https://orcid.org/0000-0001-6003-7575)
- H. Liu (ORCID: https://orcid.org/0009-0005-4037-4335)
- Yan Zhang (ORCID: https://orcid.org/0000-0001-6034-9958)
- Shuhua Ji
- Jingpeng Hou (ORCID: https://orcid.org/0000-0001-5248-7103)
Institutions
- People's Liberation Army 401 Hospital (CN)
Publication Details
- Journal
- International Journal of Women s Health
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ijwh.s565574
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00