Hyperthermia Inhibits Growth and Stemness of Esophageal Squamous Cell Carcinoma Cells Through Promoting Degradation of GLI1
Our study reveals that hyperthermia can readily destabilize GLI1 levels in ESCC cells and inhibit ESCC cells growth. This proposes new strategies for implementing hyperthermia to target GLI1 driven cancers to improve therapeutic efficacy.
Authors
- Shenglei Li (ORCID: https://orcid.org/0000-0001-8533-0081)
- Shichao Duan (ORCID: https://orcid.org/0000-0002-3177-4194)
- Xiaole Li
- Hui Qin
Institutions
- Henan Provincial People's Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Stem Cells International
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/sci/7249890
- Primary Topic
- Hedgehog Signaling Pathway Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00