Uncovering metabolic shifts: an ¹H-NMR study on the dual influence of HIV/TB coinfection and ART
ART modulates metabolic pathways disrupted by HIV/TB coinfection, showing partial improvements but leaving glucose metabolism dysregulated. These findings highlight the potential of targeted metabolic monitoring to optimize coinfection treatment strategies. Further investigations are needed in larger cohorts to validate these results and better understand coinfection pathophysiology.
Authors
- Laneke Luies (ORCID: https://orcid.org/0000-0003-4920-4090)
- Shayne Mason (ORCID: https://orcid.org/0000-0002-2945-5768)
- Robin Wood (ORCID: https://orcid.org/0000-0002-4276-7117)
- Steven Patrick Ahumada Prado (ORCID: https://orcid.org/0000-0002-1925-9069)
Institutions
- Desmond Tutu HIV Foundation (ZA)
- University of Cape Town (ZA)
- North-West University (ZA)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12879-025-12088-7
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00