Development of a Combined Clinical and Research-Developed Testing Strategy for Highly Pathogenic Avian Influenza A Virus H5
Highly pathogenic avian influenza A (H5) virus continues to spread in animals with ongoing concern for potential human transmission. We describe an adaptable H5 screening approach that integrates clinical laboratory workflows with research-developed assays. This strategy efficiently screened thousands of samples, providing a practical and scalable model for H5 surveillance.
Authors
- Soonil Kwon (ORCID: https://orcid.org/0000-0001-7847-8029)
- Vamsi Thiriveedhi (ORCID: https://orcid.org/0000-0002-7901-4645)
- Gordon C. Adams (ORCID: https://orcid.org/0000-0003-1940-9706)
- Erik H. Klontz (ORCID: https://orcid.org/0000-0002-1923-972X)
- R Laing (ORCID: https://orcid.org/0009-0005-5181-2740)
- Jacob E. Lemieux (ORCID: https://orcid.org/0000-0002-2758-4005)
- Erica S. Shenoy (ORCID: https://orcid.org/0000-0001-8086-1123)
- Sarah E. Turbett (ORCID: https://orcid.org/0000-0002-3603-8110)
- Pardis C. Sabeti (ORCID: https://orcid.org/0000-0002-9843-1890)
- John A. Branda (ORCID: https://orcid.org/0000-0002-6929-1219)
- Elyse Stachler (ORCID: https://orcid.org/0000-0002-4961-1983)
- Navid Chowdhury
- J Devlin
Institutions
- Broad Institute (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1093/ofid/ofaf744
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00