HMCN1 as a conserved biomarker of epithelial–mesenchymal transition: a cross-cancer analysis

This study identifies <i>HMCN1</i> as a novel, conserved regulator of EMT and a candidate prognostic biomarker across cancers. The findings in osteosarcoma provide a foundational rationale for developing <i>HMCN1</i> as a potential therapeutic target.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-12-12
DOI
https://doi.org/10.3389/fonc.2025.1730887
Primary Topic
Cancer Cells and Metastasis
Type
article
Field-Weighted Citation Impact
0.00
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article

HMCN1 as a conserved biomarker of epithelial–mesenchymal transition: a cross-cancer analysis

Yayun Liu, Zhi Liu, Yuanxi Leng
Frontiers in Oncology
Cancer Cells and Metastasis
article

HMCN1 as a conserved biomarker of epithelial–mesenchymal transition: a cross-cancer analysis

Yayun Liu, Zhi Liu, Yuanxi Leng
article en

Abstract

This study identifies <i>HMCN1</i> as a novel, conserved regulator of EMT and a candidate prognostic biomarker across cancers. The findings in osteosarcoma provide a foundational rationale for developing <i>HMCN1</i> as a potential therapeutic target.

Frontiers in OncologyVol. 15
Jiangxi University of Traditional Chinese Medicine (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 45%
Cancer Cells and Metastasis
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