Transformation of T-lymphoblastic lymphoma into acute myeloid leukemia after recurrence: a case report and literature review

The transformation of T-LBL into AML is exceedingly rare, and the underlying mechanisms of lineage switch remain unclear. Venetoclax combined with chemotherapy and allogeneic hematopoietic stem cell transplantation (allo-HSCT) may improve prognosis in such cases.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-12-12
DOI
https://doi.org/10.3389/fonc.2025.1673318
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Transformation of T-lymphoblastic lymphoma into acute myeloid leukemia after recurrence: a case report and literature review

Mengzhuo Yang, Xiaoqiang Zhao, Wei-Ling Mei
Frontiers in Oncology
Acute Myeloid Leukemia Research
article

Transformation of T-lymphoblastic lymphoma into acute myeloid leukemia after recurrence: a case report and literature review

Mengzhuo Yang, Xiaoqiang Zhao, Wei-Ling Mei
article en

Abstract

The transformation of T-LBL into AML is exceedingly rare, and the underlying mechanisms of lineage switch remain unclear. Venetoclax combined with chemotherapy and allogeneic hematopoietic stem cell transplantation (allo-HSCT) may improve prognosis in such cases.

Frontiers in OncologyVol. 15
First Affiliated Hospital of Henan University of Science and Technology (CN), Henan Medical University (CN)
Openalex Percentile: Top 40%
Acute Myeloid Leukemia Research
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