Targeting macrophage JAK3/STAT3 signaling with tectochrysin: a novel therapeutic strategy to ameliorate bone erosion and synovitis in rheumatoid arthritis
Tectochrysin may be a novel RA therapeutic agent, likely acting via macrophage JAK/STAT pathway inhibition, with promising clinical potential.
Authors
- Wei Huang (ORCID: https://orcid.org/0000-0002-1775-6512)
- Lianying Hu
- Shuyi Cheng (ORCID: https://orcid.org/0000-0002-1999-8021)
- Jianjun Chu
- Pin Pan
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s13018-025-06481-w
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00