Insulin resistance and its association with coronary heart disease: insights from bioinformatics analysis
In this large hospital-based cross-sectional sample, non-insulin-based IR surrogates were positively associated with the prevalence of CHD and may help identify groups with a higher likelihood of having CHD. Glycemic pathways and physical inactivity emerged as important correlates of these associations and deserve further evaluation in longitudinal studies.
Authors
- Mingrong Liu
- Xinyue Lu (ORCID: https://orcid.org/0000-0002-0550-1141)
- Xiaoxu Xie (ORCID: https://orcid.org/0000-0002-3103-3724)
- Yang Song (ORCID: https://orcid.org/0000-0001-7716-9216)
- Aina Li
- Xinqi Zhou (ORCID: https://orcid.org/0000-0002-5032-9141)
- Shiying Lin (ORCID: https://orcid.org/0000-0002-9819-9059)
- Hang Zeng
- Huangyuan Li (ORCID: https://orcid.org/0000-0003-1799-1528)
- Siying Wu (ORCID: https://orcid.org/0000-0003-0440-7636)
- Shaowei Lin
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.3389/fendo.2025.1730801
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China