Identification and validation of biomarkers related to centrosome replication in ulcerative colitis based on bulk transcriptome, single-cell RNA sequencing and experiments
Six CARGs-TEX11, SLC16A1, OVOL1, EDNRA, HEPACAM2, and SPIRE2-were identified as potential biomarkers with significant implications in UC pathogenesis.
Authors
- Zhongqin Dang
- Zhenhuan Yang
- Xingxing Wu
- Tingting Huang (ORCID: https://orcid.org/0000-0001-5001-0782)
- Yuliang Wang (ORCID: https://orcid.org/0000-0001-6174-6365)
- Sipei Nie (ORCID: https://orcid.org/0000-0002-9993-8941)
- Lei Luo (ORCID: https://orcid.org/0009-0005-9867-316X)
- Xiuxia Wu
Institutions
- Henan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1627926
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00