Serum asprosin level is significantly lower in patients with liver cirrhosis than in those with non-cirrhotic chronic liver diseases
These findings suggest that asprosin may be involved in the progression of liver cirrhosis, with potential as a novel biomarker for its diagnosis and prognosis and implications for fibrosis management. However, further prospective studies are needed to clarify the causal relationship between asprosin and liver cirrhosis and explore its underlying molecular mechanisms.
Authors
- Xinli Zhou (ORCID: https://orcid.org/0000-0003-0294-2002)
- Sichao Wang (ORCID: https://orcid.org/0000-0003-0931-7883)
- Tao Li (ORCID: https://orcid.org/0000-0002-9038-4794)
- Shujun Zhang (ORCID: https://orcid.org/0000-0003-0719-8534)
- Li Chen (ORCID: https://orcid.org/0000-0002-0201-3863)
- Yan Wang (ORCID: https://orcid.org/0000-0002-1743-6383)
Institutions
- Shandong University (CN)
- University of Jinan (CN)
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Ministry of Education (TH)
- Qilu Hospital of Shandong University (CN)
- Shandong Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.3389/fendo.2025.1691224
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong University
- Qilu Hospital of Shandong University