Identification and validation of ubiquitination-associated genes of senile osteoporosis based on bioinformatics analysis
This study successfully identified RPS27A and UBE2E1 as key biomarkers for SOP, demonstrating their diagnostic potential and involvement in important biological pathways and immune responses, thus offering new prospects for therapeutic interventions.
Authors
- Yinghui Guan (ORCID: https://orcid.org/0000-0003-1801-8332)
- Jing Bao-qian
- Xiyue Cheng
- Yan Cao (ORCID: https://orcid.org/0000-0001-9780-4221)
- Jing Zhao (ORCID: https://orcid.org/0000-0003-4655-997X)
- Junchuan Liu (ORCID: https://orcid.org/0000-0002-5759-1214)
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1629276
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00