A proteomic profile correlates with salivary gland inflammation and disease-associated antibodies in Sjögren’s disease
We define a validated serum proteomic signature that reflects local glandular inflammation and correlates with genetic and serological features. The 'Sjögren protein score' holds promise as a noninvasive biomarker for the diagnosis of SjD.
Authors
- Sara Magnusson Bucher
- Malin V. Jonsson (ORCID: https://orcid.org/0000-0001-5655-5513)
- Juliana Imgenberg‐Kreuz (ORCID: https://orcid.org/0000-0002-7230-8990)
- Elina Richardsdotter Andersson (ORCID: https://orcid.org/0000-0002-3030-2048)
- Silke Appel (ORCID: https://orcid.org/0000-0002-2199-2315)
- Marie Fischer (ORCID: https://orcid.org/0000-0001-9047-3650)
- Per Eriksson (ORCID: https://orcid.org/0000-0002-5635-2692)
- Gunnel Nordmark (ORCID: https://orcid.org/0000-0002-3829-7431)
- Katrine Brække Norheim (ORCID: https://orcid.org/0000-0002-3770-8139)
- Lauro Meneghel (ORCID: https://orcid.org/0000-0001-7758-9165)
- Marie Wahren‐Herlenius (ORCID: https://orcid.org/0000-0002-0915-7245)
- Elisabeth Mæland
- Marika Kvarnström (ORCID: https://orcid.org/0000-0002-4948-8380)
- Helena Forsblad‐d’Elia (ORCID: https://orcid.org/0000-0001-7871-5303)
- Peter Olsson (ORCID: https://orcid.org/0000-0003-1774-1828)
- Ingrid Skelton Kockum (ORCID: https://orcid.org/0000-0002-0867-4726)
- Roland Jonsson (ORCID: https://orcid.org/0000-0002-9588-0260)
- Kathrine Skarstein
- Johannes Mofors (ORCID: https://orcid.org/0000-0003-1873-7169)
- Daniel Hammenfors
- Roald Omdal (ORCID: https://orcid.org/0000-0002-6051-4658)
- Thomas Mandl (ORCID: https://orcid.org/0000-0002-7143-7088)
- Albin Björk
- Svein Joar Auglænd Johnsen
Institutions
- Linköping University (SE)
- Uppsala University (SE)
- Karolinska University Hospital (SE)
- Lund University (SE)
- Örebro University (SE)
- Stavanger University Hospital (NO)
- Science for Life Laboratory (SE)
- Haukeland University Hospital (NO)
- Karolinska Institutet (SE)
- University of Bergen (NO)
- University of Gothenburg (SE)
Publication Details
- Journal
- Annals of the Rheumatic Diseases
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1016/j.ard.2025.11.013
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Servier