Thyrotoxicosis-Induced Chordal Rupture Causing Severe Mitral Regurgitation
Thyrotoxicosis can cause chordal rupture and flail leaflet. Repair is preferred, but replacement is appropriate when repair is not durable. Management requires endocrine-cardiac coordination and individualized antithrombotic therapy. Expect early ejection-fraction decline after surgical correction.
Authors
- Ahmed Abu‐Haniyeh (ORCID: https://orcid.org/0000-0002-7932-9348)
- Gopal P. Acharya (ORCID: https://orcid.org/0009-0007-7444-8966)
- Aws Polina (ORCID: https://orcid.org/0000-0003-4021-9026)
- Rohit Pandit (ORCID: https://orcid.org/0000-0002-2567-3098)
- Bezawit Zewde
Institutions
- Salisbury University (US)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1016/j.jaccas.2025.106426
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00