Oral <i>Akkermansia muciniphila</i> may ameliorates immune dysregulation in a murine model of streptozotocin-induced type 1 diabetes
Short-term intervention with <i>A. muciniphila</i> has shown positive effects on immune response parameters, exemplified by Treg-mediated restoration of immune tolerance, which may be associated with intestinal barrier enhancement and the decreased abundance of intestinal <i>Actinobacteria</i>.
Authors
- Qiuli Chen (ORCID: https://orcid.org/0000-0001-8531-6175)
- Xia Lin (ORCID: https://orcid.org/0000-0002-2975-1532)
- Jun Zhang (ORCID: https://orcid.org/0000-0003-2633-1521)
- Bo Huang (ORCID: https://orcid.org/0000-0001-8476-1138)
- Huamei Ma
- Yanhong Li (ORCID: https://orcid.org/0009-0004-8495-7287)
- Song Guo
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2025-12-12
- DOI
- https://doi.org/10.4239/wjd.v16.i12.111771
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81