Clinical study of separation surgery combined with intraoperative vertebroplasty and 125I seeds implantation for spinal metastases from lung adenocarcinoma with epidural spinal cord compression

SSVPI is an optimized treatment for lung adenocarcinoma-related MESCC. It provides immediate spinal cord decompression and stabilization, concurrent intraoperative <sup>125</sup>I seeds implantation for early and sustained radiotherapy, and avoids delayed postoperative radiation and complications associated with external beam therapy. This approach enhances local tumor control while preserving neurological function and improving quality of life.

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Publication Details

Journal
World Journal of Surgical Oncology
Published
2025-12-12
DOI
https://doi.org/10.1186/s12957-025-04148-8
Primary Topic
Management of metastatic bone disease
Type
article
Field-Weighted Citation Impact
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article

Clinical study of separation surgery combined with intraoperative vertebroplasty and 125I seeds implantation for spinal metastases from lung adenocarcinoma with epidural spinal cord compression

Zhou Huang, N. Haq, Tiying Wang, Cao Wang et al.
World Journal of Surgical Oncology
Management of metastatic bone disease
article

Clinical study of separation surgery combined with intraoperative vertebroplasty and 125I seeds implantation for spinal metastases from lung adenocarcinoma with epidural spinal cord compression

Zhou Huang, N. Haq, Tiying Wang, Cao Wang, Dongqi Li, Jing Zhang, Hongpu Sun, Bin Fan, Ya Zhang, Xiang Ma, Yan Liu, Zuozhang Yang, Xiaohui Yang, Lei Han, Tao Yuan, Lu Cai, Donghui Xu, Weiquan Wang
article en

Abstract

SSVPI is an optimized treatment for lung adenocarcinoma-related MESCC. It provides immediate spinal cord decompression and stabilization, concurrent intraoperative <sup>125</sup>I seeds implantation for early and sustained radiotherapy, and avoids delayed postoperative radiation and complications associated with external beam therapy. This approach enhances local tumor control while preserving neurological function and improving quality of life.

World Journal of Surgical OncologyVol. 24(1)
Kunming Medical University (CN)
Openalex Percentile: Top 41%
Management of metastatic bone disease
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