Clinical significance of the S204 phosphorylation of the Smad3 protein in combination with Ki67 for the metastasis and prognosis of gastric cancer
High expression of Ki67 and high expression of pSmad3L(S204) are independent risk factors for the prognosis of patients with GC, and the combined analysis of Ki67 and pSmad3L(S204) can help to improve the risk prediction.
Authors
- Ling-Yu Luo (ORCID: https://orcid.org/0000-0002-1090-0198)
- Qing Hu (ORCID: https://orcid.org/0000-0001-6047-4935)
- Rensheng Chen
- Pei Guo
- Hongtao Sun (ORCID: https://orcid.org/0000-0001-8621-3215)
- Deqiang Huang
- Yi-Hui Kang
- Shi-Lin Lv (ORCID: https://orcid.org/0009-0009-2747-8171)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Southern Medical University Shenzhen Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1186/s12876-025-04485-8
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00