Longitudinal [18F]LW223 PET imaging of macrophage-driven inflammation following myocardial infarction in a rat model: implications for left ventricular remodelling

[<sup>18</sup>F]LW223 identifies a persistent and predominantly macrophage-driven inflammatory response with early [<sup>18</sup>F]LW223 infarct binding associated with later cardiac dysfunction.

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Publication Details

Journal
European Journal of Nuclear Medicine and Molecular Imaging
Published
2025-12-12
DOI
https://doi.org/10.1007/s00259-025-07691-4
Citations
1
Primary Topic
Cardiac Fibrosis and Remodeling
Type
article
Field-Weighted Citation Impact
1.39

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article

Longitudinal [18F]LW223 PET imaging of macrophage-driven inflammation following myocardial infarction in a rat model: implications for left ventricular remodelling

Andrew Sutherland, Lachlan J. N. Waddell, Thomas M. Wishart, Ana Clara Juan De Albuquerque et al.
1 citations
European Journal of Nuclear Medicine and Molecular Imaging
Cardiac Fibrosis and Remodeling
1.39
article

Longitudinal [18F]LW223 PET imaging of macrophage-driven inflammation following myocardial infarction in a rat model: implications for left ventricular remodelling

Andrew Sutherland, Lachlan J. N. Waddell, Thomas M. Wishart, Ana Clara Juan De Albuquerque, Judit Aguilar Martí, Sally L. Pimlott, Nicholas L. Mills, Agne Knyzeliene, Dominic Kurian, Mark G. MacAskill, Timaeus E. F. Morgan, Carlos J. Alcaide‐Corral, Christophe Lucatelli, Adriana Tavares, Adrian Thomson, Marc R. Dweck, Takeshi Fujisawa, E. Chui, David E. Newby, Catriona Wimberley, Viktória Balogh, Victoria J. M. Reid
article en
1 citations

Abstract

[<sup>18</sup>F]LW223 identifies a persistent and predominantly macrophage-driven inflammatory response with early [<sup>18</sup>F]LW223 infarct binding associated with later cardiac dysfunction.

European Journal of Nuclear Medicine and Molecular ImagingVol. 53(5)
Roslin Institute (GB), NHS Greater Glasgow and Clyde (GB), Institute of Particle Physics (CA), Nottingham Trent University (GB), University of Glasgow (GB), University of Edinburgh (GB)
British Heart Foundation
Openalex Percentile: Top 13%
Cardiac Fibrosis and Remodeling
1.39
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