THE INAPRES (Indonesia Preeclampsia Study): impact of eclampsia on maternal and perinatal outcomes among women with preeclampsia: findings from a National Multicenter Cohort

In this Indonesian multicenter cohort, preeclamptic pregnancies complicated by eclampsia were associated with significantly higher severe maternal and perinatal morbidity compared to those without eclampsia. These findings underscore the critical importance of early detection and prompt management of preeclampsia, including the timely use of MgSO4 for seizure prophylaxis, strict blood pressure control, and timely delivery of patients with severe preeclampsia, to prevent progression to eclampsia and mitigate adverse outcomes.

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Publication Details

Journal
AJOG Global Reports
Published
2025-12-12
DOI
https://doi.org/10.1016/j.xagr.2025.100596
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
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article

THE INAPRES (Indonesia Preeclampsia Study): impact of eclampsia on maternal and perinatal outcomes among women with preeclampsia: findings from a National Multicenter Cohort

Rozi Aditya Aryananda, Muhammad Ilham Aldika Akbar, Wiku Andonotopo, Dhanny Primantara Johari Santoso et al.
AJOG Global Reports
Pregnancy and preeclampsia studies
article

THE INAPRES (Indonesia Preeclampsia Study): impact of eclampsia on maternal and perinatal outcomes among women with preeclampsia: findings from a National Multicenter Cohort

Rozi Aditya Aryananda, Muhammad Ilham Aldika Akbar, Wiku Andonotopo, Dhanny Primantara Johari Santoso, Anak Agung Gede Putra Wiradyana, Gustaaf Dekker, Manggala Pasca Wardhana, Ernawati Ernawati, Ruth Widhiati Raharjo Putri
article en

Abstract

In this Indonesian multicenter cohort, preeclamptic pregnancies complicated by eclampsia were associated with significantly higher severe maternal and perinatal morbidity compared to those without eclampsia. These findings underscore the critical importance of early detection and prompt management of preeclampsia, including the timely use of MgSO4 for seizure prophylaxis, strict blood pressure control, and timely delivery of patients with severe preeclampsia, to prevent progression to eclampsia and mitigate adverse outcomes.

AJOG Global ReportsVol. 6(1)
Surya University (ID), Universitas Airlangga (ID), Erasmus MC (NL), Universitas Garut (ID), Community Health Systems - Lutheran Hospital (US), Universitas Dr. Soetomo (ID), Borneo Orangutan Survival Foundation (ID), The University of Adelaide (AU)
Openalex Percentile: Top 49%
Pregnancy and preeclampsia studies
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THE INAPRES (Indonesia Preeclampsia Study): impact of eclampsia on maternal and perinatal outcomes among women with preeclampsia: findings from a National Multicenter Cohort — Rozi Aditya Aryananda, Muhammad Ilham Aldika Akbar, et al. · AJOG Global Reports (2025) | TGRS Research Map | TGRS