Herpes Zoster Reactivation in Patients with Coronary Artery Disease
The association between varicella-zoster virus (VZV) reactivation and coronary artery disease (CAD) remains uncertain. We enrolled 107 patients (mean age 66.5±10.8 years; 72% male) who underwent coronary angiography due to suspected CAD and assessed subclinical VZV reactivation via salivary VZV PCR. Patients were divided into three groups: acute coronary syndrome, chronic coronary syndrome, and insignificant CAD. VZV DNA was detected in three patients (3%) -one in the acute group and two in the chronic group (<i>P</i>=0.469). Although not statistically significant, these findings warrant further investigation into the potential link between VZV reactivation and CAD.
Authors
- Sang‐Oh Lee (ORCID: https://orcid.org/0000-0003-1381-8787)
- Seung-Beom Kim (ORCID: https://orcid.org/0009-0005-5348-4074)
- Hyo‐Ju Son (ORCID: https://orcid.org/0000-0001-8015-6416)
- In Tae Moon (ORCID: https://orcid.org/0000-0002-3847-0150)
- Ji‐Soo Kwon (ORCID: https://orcid.org/0000-0001-6945-6100)
- Sung‐Han Kim (ORCID: https://orcid.org/0000-0002-6596-8253)
- Kyung Hwa Jung (ORCID: https://orcid.org/0000-0002-2310-0958)
Institutions
- Ulsan College (KR)
- Eulji University (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR)
- Inje University Sanggye Paik Hospital (KR)
- Daejeon Eulji Medical Center, Eulji University (KR)
Publication Details
- Journal
- Infection and Chemotherapy
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3947/ic.2025.0056
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00