Interplay of IL‐6, GDF‐15 and Sarcopenia in Patients With Bladder Cancer Undergoing Radical Cystectomy and Its Implications on Survival
These findings highlight the interplay between IL-6, GDF-15, sarcopenia and tumour progression, suggesting that IL-6 and GDF-15 may serve as valuable prognostic biomarkers and potential therapeutic targets. Further research is warranted to explore targeted therapeutic strategies aimed at mitigating sarcopenia and systemic inflammation in this patient population.
Authors
- Peter J. Siska (ORCID: https://orcid.org/0000-0002-1521-6213)
- Simon Engelmann (ORCID: https://orcid.org/0000-0003-3810-3307)
- Maximilian Haas (ORCID: https://orcid.org/0000-0003-3132-0130)
- Roman Mayr (ORCID: https://orcid.org/0000-0003-1796-3260)
- Francesco Del Giudice (ORCID: https://orcid.org/0000-0002-9414-6937)
- Christoph Nießen (ORCID: https://orcid.org/0000-0003-0245-6389)
- Christoph Pickl
- Renate Pichler (ORCID: https://orcid.org/0000-0001-5286-9048)
- Miodrag Gužvić (ORCID: https://orcid.org/0000-0001-8089-3969)
- Maximilian Burger (ORCID: https://orcid.org/0009-0005-5013-9435)
- Emily Rinderknecht (ORCID: https://orcid.org/0009-0002-7283-5237)
- Felix Kasparbauer
Institutions
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- University Hospital Regensburg (DE)
- Caritas-Krankenhaus St. Josef (DE)
- University of Regensburg (DE)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/jcsm.70146
- Citations
- 1
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.80