Loeffler Syndrome in FIP1L1-PDGFRA-Positive Myeloid Neoplasm
Cardiac involvement in hypereosinophilic syndromes requires multidisciplinary management combining cytoreductive therapy, anticoagulation when thrombus is present, and serial cardiac magnetic resonance. Testing for FIP1L1-platelet-derived growth factor receptor α is disease-defining and therapy-guiding given the marked response to imatinib.
Authors
- Carlos Sánchez Sánchez
- Daniel Gaitán Román (ORCID: https://orcid.org/0000-0002-0813-0489)
- Cristóbal Urbano Carrillo
- Marta Alcalá Ramírez del Puerto
- Isabel Piñero Uribe
Institutions
- Hospital Regional Universitario de Málaga (ES)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1016/j.jaccas.2025.106296
- Primary Topic
- Eosinophilic Disorders and Syndromes
- Type
- article
- Field-Weighted Citation Impact
- 0.00