Excessive IL-4 environment enhances osteoclastogenesis and modulates inflammatory cell differentiation in bone loss associated with food allergic enteropathy
The present study provides a new perspective on a poorly understood mechanism of osteoporosis in severe allergies, suggesting the importance of maintaining bone health in allergic patients, including food allergies.
Authors
- Michio Tomura
- Atsushi Furuhata
- Masato Tamai
- Akihiko Itoh
- Naoki Shimojo (ORCID: https://orcid.org/0000-0002-8076-0493)
- Kohei Soga (ORCID: https://orcid.org/0000-0001-7364-6724)
- Satoshi Hachimura (ORCID: https://orcid.org/0000-0002-4475-781X)
- Fusako Yamazaki
- Shigeru Kakuta (ORCID: https://orcid.org/0000-0002-5900-1425)
- Masaaki Hashiguchi (ORCID: https://orcid.org/0000-0002-3359-4488)
- Haruyo Nakajima‐Adachi (ORCID: https://orcid.org/0000-0003-2008-2501)
- Shuji Matsuoka
- Shotaro Nakamura (ORCID: https://orcid.org/0000-0001-8166-2599)
- Satoru Uno
- Tomoyuki Hoshino
- K Takane
- Kosuke Nishitsuji
- Ryo Isogaki
Institutions
- Tokyo University of Agriculture (JP)
- Osaka Ohtani University (JP)
- Juntendo University (JP)
- Chiba University Hospital (JP)
- Neuromorphometrics (United States) (US)
- Oji Holdings (Japan) (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Allergology International
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1016/j.alit.2025.11.007
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00