Real-world evidence on diagnostic pathways and biopsy optimization for PD-L1 and molecular profiling in advanced non-small cell lung cancer: A four-year cohort analysis
Minimally invasive techniques, particularly EBUS and EUS-B, shortened diagnostic delays, ensured adequate biomarker sampling, and enabled earlier initiation of systemic therapy. Since the time-to-diagnosis was independently associated with survival, these approaches may have indirectly contributed to improved outcomes. Our findings highlight the importance of streamlining diagnostic pathways and expanding access to endoscopic methods to optimize care in advanced NSCLC.
Authors
- Luís Vaz Rodrigues (ORCID: https://orcid.org/0000-0001-5929-6078)
- Joana das Flores Duarte (ORCID: https://orcid.org/0000-0001-7175-756X)
- Rosa Cordovilla (ORCID: https://orcid.org/0000-0001-8907-1072)
- Luís Taborda‐Barata (ORCID: https://orcid.org/0000-0001-6649-8890)
- Vítor Sousa (ORCID: https://orcid.org/0000-0003-3219-1078)
- Joana Oliveira (ORCID: https://orcid.org/0000-0003-3267-095X)
Institutions
- University of Beira Interior (PT)
- Hospitais da Universidade de Coimbra (PT)
- Complejo Hospitalario de Salamanca (ES)
- Hospital Beatriz Ângelo (PT)
- University of Coimbra (PT)
Publication Details
- Journal
- Jornal Brasileiro de Pneumologia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.36416/1806-3756/e20250188
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00