A Highly Stable Lanthanide-Organic Framework for Ultrasensitive Dynamic Luminescence Detection of Quercetin
Quercetin is widely regarded as a promising therapeutic agent with multifaceted protective effects on the cardiovascular system, but its luminescence-based detection in actual samples remains challenging due to weak host-guest interactions. In this work, a highly stable mixed ligand lanthanide-organic framework ({[Eu<sub>2</sub>(BETC)(NDC)(H<sub>2</sub>O)(DMF)]·2.5H<sub>2</sub>O}<sub><i>n</i></sub>, <b>HBNU</b>-<b>21</b>-<b>Eu</b>) was prepared through a solvothermal reaction using 1,2,4,5-benzenetetracarboxylic acid (H<sub>4</sub>BETC) and 1,4-naphthalenedicarboxylic acid (H<sub>2</sub>NDC) as mixed ligands and Eu<sup>3+</sup> ion as a node. <b>HBNU</b>-<b>21</b>-<b>Eu</b> displays good pH/solvent/thermo stability and intense red luminescence with a high quantum yield of 70.2%. Rapid luminescence detection of quercetin was successfully achieved within 30 s through a highly efficient dynamic quenching process, with a high quenching constant of 5.08 × 10<sup>4</sup> M<sup>-1</sup> and a low detection limit of 0.57 μM. The actual sample detection capabilities of quercetin in tap water samples and jasmine tea were verified with satisfactory recovery rates.
Authors
- Hui Min (ORCID: https://orcid.org/0000-0001-6415-3557)
- F. Ye (ORCID: https://orcid.org/0009-0002-0066-7609)
- Nian Zhao (ORCID: https://orcid.org/0000-0001-6841-737X)
- Ruo-Bing Shi
- Meiyi Huang
Institutions
- CAS Key Laboratory of Urban Pollutant Conversion (CN)
- Hubei Normal University (CN)
Publication Details
- Journal
- Inorganic Chemistry
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1021/acs.inorgchem.5c04666
- Citations
- 1
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.54