LAMCAK pilot study: urinary cathepsin K as a potential biomarker in lymphangioleiomyomatosis

<b>Pathophysiology of LAM could be partly explained by abnormal overexpression of proteases such as cathepsin K (CatK). In this pilot study, we found an increase in pro-CatK levels in LAM patients compared to healthy female volunteers.</b> https://bit.ly/46U3vAG.

Authors

Institutions

Publication Details

Journal
ERJ Open Research
Published
2025-12-11
DOI
https://doi.org/10.1183/23120541.00279-2025
Primary Topic
Tuberous Sclerosis Complex Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

LAMCAK pilot study: urinary cathepsin K as a potential biomarker in lymphangioleiomyomatosis

Thomas Flament, Lise Vanderlynden, S. Marchand‐Adam, Marion Pronost et al.
ERJ Open Research
Tuberous Sclerosis Complex Research
article

LAMCAK pilot study: urinary cathepsin K as a potential biomarker in lymphangioleiomyomatosis

Thomas Flament, Lise Vanderlynden, S. Marchand‐Adam, Marion Pronost, Gilles Lalmanach, Fabien Lecaille
article en

Abstract

<b>Pathophysiology of LAM could be partly explained by abnormal overexpression of proteases such as cathepsin K (CatK). In this pilot study, we found an increase in pro-CatK levels in LAM patients compared to healthy female volunteers.</b> https://bit.ly/46U3vAG.

ERJ Open ResearchVol. 12(2)
Université de Tours (FR), Inserm (FR), Centre de recherche en Epidémiologie et Santé des Populations (FR)
Openalex Percentile: Top 51%
Tuberous Sclerosis Complex Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.