Paediatric Stevens-Johnson syndrome and toxic epidermal necrolysis: patterns and outcomes in a retrospective Pakistani cohort
Paediatric drug-induced SJS/TEN remains a critical concern, particularly due to commonly prescribed antibiotics and NSAIDs. High mortality in TEN cases and predominant use of supportive therapy highlight the need for clear paediatric treatment protocols. Local data on the role of early immunomodulatory therapy are limited, indicating a need for further research on optimal early interventions to improve outcomes.
Authors
- Amber Tahir (ORCID: https://orcid.org/0000-0001-6335-0516)
- Arshalooz Jamila Rahman (ORCID: https://orcid.org/0009-0000-4434-089X)
- Saadia Tabassum (ORCID: https://orcid.org/0000-0002-5428-3603)
- Amala Khan
- Farwa Ayub (ORCID: https://orcid.org/0009-0008-9004-8716)
- Ambreen Sonawalla
- Shahbaz Mehmood (ORCID: https://orcid.org/0009-0003-6978-5264)
Institutions
- Aga Khan University (PK)
- Boston Children's Hospital (US)
- York General Hospital (US)
- Aga Khan University Hospital (PK)
- Thai Health Promotion Foundation (TH)
- York District Hospital (US)
Publication Details
- Journal
- BMJ Paediatrics Open
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjpo-2025-003984
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00