A Case Report of Unilateral OPA3-Related Dominant Optic Atrophy
This represents the first documented case of unilateral <i>OPA3</i>-related DOA, challenging the long-held view that DOA is inherently bilateral. Recognition of such atypical presentations may expand the clinical spectrum of <i>OPA3</i>-related disease and inform diagnostic and genetic counseling approaches for patients with unilateral optic neuropathy.
Authors
- Haoran Charles Li
- Matthew Ware (ORCID: https://orcid.org/0000-0002-3251-1759)
- Jonathan Andrew Micieli (ORCID: https://orcid.org/0000-0003-4911-9152)
Institutions
- University of Toronto (CA)
- Kensington Health (CA)
Publication Details
- Journal
- Case Reports in Ophthalmology
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1159/000550003
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00